{"id":698,"date":"2014-10-07T16:55:09","date_gmt":"2014-10-07T08:55:09","guid":{"rendered":"http:\/\/www.tculs.tcu.edu.tw\/?page_id=698"},"modified":"2014-10-07T16:55:09","modified_gmt":"2014-10-07T08:55:09","slug":"%e8%a8%b1%e8%b1%aa%e4%bb%81-%e5%8a%a9%e7%90%86%e6%95%99%e6%8e%88","status":"publish","type":"page","link":"https:\/\/bmse.tcu.edu.tw\/?page_id=698","title":{"rendered":"\u8a31\u8c6a\u4ec1 \u6559\u6388"},"content":{"rendered":"

\t\t\t\t\"image\"<\/b><\/p>\n

\u8a31\u8c6a\u4ec1\u6559\u6388<\/strong><\/p>\n

\uff0e\u806f\u7d61\u65b9\u5f0f\uff1a<\/b>\u6821\u5167\u5206\u6a5f2643\u3001\u5be6\u9a57\u5ba4\u5206\u6a5f2644
\n\uff0e\u8fa6\u516c\u5ba4<\/b>\/<\/b>\u5be6\u9a57\u5ba4\u4f4d\u7f6e\uff1a<\/b>D904\/D923
\n\uff0e<\/b>Email<\/b>\uff1a<\/b>hjhsu32@mail.tcu.edu.tw<\/a>
\n\uff0e\u7db2\u9801\uff1a<\/b>http:\/\/hsulab923.webs.com<\/a>
\n<\/b>\uff0e\u5b78\u6b77\uff1a<\/b>\u967d\u660e\u5927\u5b78\u91ab\u5b78\u5de5\u7a0b\u7814\u7a76\u6240\u535a\u58eb
\n\uff0e\u5c08\u9577\uff1a<\/b>\u86cb\u767d\u8cea\u5438\u9644\u3001\u8a08\u7b97\u751f\u7269\u5b78\u3001\u5206\u5b50\u751f\u7269\u7269\u7406
\n\uff0e\u958b\u8a2d\u8ab2\u7a0b\uff1a<\/b>\u666e\u901a\u7269\u7406\u5b78\u3001\u85e5\u7269\u8a2d\u8a08\u7406\u8ad6\u8207\u5be6\u4f8b\u3001\u751f\u7269\u5de8\u5206\u5b50\u63a2\u7a76\u5206\u6790
\n\uff0e\u5be6\u9a57\u5ba4\u540d\u7a31\uff1a<\/b>\u751f\u7269\u7269\u7406\u66a8\u7d50\u69cb\u751f\u7269\u5be6\u9a57\u5ba4
\n\uff0e\u7814\u7a76\u9818\u57df\u7c21\u4ecb\uff1a
\n<\/b>(1) \u6a21\u64ec\u75c5\u6bd2\u96e2\u5b50\u901a\u9053\u7d50\u69cb
\n\u6b64\u901a\u9053\u86cb\u767d\u53ef\u5728\u5bbf\u4e3b\u7d30\u80de\u819c\u4e0a\u5f62\u6210\u9078\u64c7\u6027\u96e2\u5b50\u901a\u9053\uff0c\u4e26\u53ef\u4ee5\u7528\u4f86\u4f5c\u70ba\u65b0\u7684\u6297\u75c5\u6bd2\u4f5c\u7528\u6a19\u9776\u3002
\n\u76ee\u524d\u9032\u884c\u4e2d\u7684\u96e2\u5b50\u901a\u9053\u6709\uff1a
\nSARS-CoV, HCV, and HIV-1.<\/p>\n

(2) \u53d7\u914d\u9ad4\u8abf\u63a7\u96e2\u5b50\u901a\u9053\u7684\u6a5f\u5236\u7814\u7a76
\n\u6b64\u96e2\u5b50\u901a\u9053\u7684\u958b\u95dc\u662f\u7531\u5316\u5b78\u8a0a\u606f\u8207\u53d7\u9ad4\u7684\u7d50\u5408\u4f86\u8abf\u63a7\u3002
\n\u76f8\u95dc\u7684\u554f\u984c\u63a2\u8a0e\uff1a\u96e2\u5b50\u901a\u9053\u7684\u9078\u64c7\u6027\u3001\u958b\u95dc\u6a5f\u5236\u7b49\u3002\u00a0<\/b><\/p>\n

\uff0e\u8fd1\u5e74\u7814\u7a76\u8a08\u756b\uff1a<\/b>\u00a0<\/b>\u00a0<\/b>\u00a0<\/b><\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u5e8f\u865f<\/td>\n\u88dc\u52a9\u6216\u59d4\u8a17\u6a5f\u69cb<\/td>\n\u8a08\u756b\u540d\u7a31<\/td>\n\u8d77\u8a16\u5e74\u6708<\/td>\n\u64d4\u4efb\u7684\u5de5\u4f5c<\/td>\n<\/tr>\n
1<\/td>\n\u79d1\u6280\u90e8<\/td>\n\u7d50\u69cb\u70ba\u57fa\u790e\u4e4b\u80dc\u80bd\u85e5\u7269\u6539\u826f\u4ee5\u52a0\u5f37\u6291\u5236\u6557\u8840\u75c7\u53ca\u5176\u5206\u5b50\u6291\u5236\u6a5f\u5236\u4e4b\u63a2\u8a0e<\/td>\n2018\/8\/1~<\/p>\n

2019\/7\/31<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
2<\/td>\n\u79d1\u6280\u90e8<\/td>\n\u884d\u751f\u81eaCXCL8\u4e4b\u62ee\u6297\u80dc\u80bd\u5c0d\u767c\u708e\u5f15\u8d77\u7684\u8179\u819c\u708e\u548c\u4e73\u817a\u764c\u8f49\u79fb\u4e4b\u5f71\u97ff(2\/2)<\/td>\n2017\/8\/1~<\/p>\n

2018\/7\/31<\/td>\n

\u5171\u540c\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
3<\/td>\n\u6148\u6fdf\u91ab\u7642\u5fd7\u696d<\/td>\n\u7d30\u80de\u6fc0\u7d20 IL10 \u884d\u751f\u4e4b\u80dc\u80bd\u85e5\u7269\u958b\u767c\u4ee5\u6291\u5236\u6dcb\u5df4\u76f8\u95dc\u60e1\u6027\u816b\u7624\u4e4b\u7814\u7a76(2\/3)<\/td>\n2018\/7\/1~<\/p>\n

2019\/6\/30<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
4<\/td>\n\u79d1\u6280\u90e8<\/td>\n\u884d\u751f\u81eaCXCL8\u4e4b\u62ee\u6297\u80dc\u80bd\u5c0d\u767c\u708e\u5f15\u8d77\u7684\u8179\u819c\u708e\u548c\u4e73\u817a\u764c\u8f49\u79fb\u4e4b\u5f71\u97ff(1\/2)<\/td>\n2016\/8\/1~<\/p>\n

2017\/7\/31<\/td>\n

\u5171\u540c\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
5<\/td>\n\u6148\u6fdf\u91ab\u7642\u5fd7\u696d<\/td>\n\u7d30\u80de\u6fc0\u7d20 IL10 \u884d\u751f\u4e4b\u80dc\u80bd\u85e5\u7269\u958b\u767c\u4ee5\u6291\u5236\u6dcb\u5df4\u76f8\u95dc\u60e1\u6027\u816b\u7624\u4e4b\u7814\u7a76(1\/3)<\/td>\n2017\/7\/1~<\/p>\n

2018\/6\/30<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
6<\/td>\n\u8ca1\u5718\u6cd5\u4eba\u5de5\u696d\u6280\u8853\u7814\u7a76\u9662<\/td>\n\u7d30\u80de\u56e0\u5b50\u53d7\u9ad4\u884d\u751f\u4e4b\u80dc\u80bd\u56fa\u5b9a\u5316\u6750\u6599\u88fd\u5099\u4ee5\u6291\u5236\u6d17\u814e\u767c\u708e\u53cd\u61c9\u53ca\u56b4\u91cd\u6557\u8840\u75c7<\/td>\n2016\/12\/1~<\/p>\n

2017\/11\/30<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
7<\/td>\n\u6148\u6fdf\u57fa\u91d1\u6703<\/td>\n\u4eba\u985e\u591a\u5df4\u80faD3\u53d7\u9ad4\u6d3b\u5316\u6a5f\u5236\u7406\u8ad6\u6a21\u64ec\u8207\u5be6\u9a57\u7814\u7a76<\/td>\n2016\/8\/1~<\/p>\n

2017\/7\/31<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
8<\/td>\n\u79d1\u6280\u90e8<\/td>\nG-\u86cb\u767d\u5076\u5408\u53d7\u9ad4\u8207\u5176\u914d\u9ad4\u7d50\u5408\u6a5f\u5236\u65bc\u539f\u5b50\u8207\u5206\u5b50\u4f4d\u968e\u4e4b\u7406\u8ad6\u6a21\u64ec\u8207\u5be6\u9a57\u7814\u7a76 (II)(III)<\/td>\n2016\/8\/1~<\/p>\n

2017\/7\/31<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
9<\/td>\n\u6148\u6fdf\u91ab\u7642\u5fd7\u696d<\/td>\n\u7d30\u80de\u6fc0\u7d20IL10\u884d\u751f\u4e4b\u80dc.\u85e5\u7269\u958b\u767c\u4ee5\u6291\u5236EBV\u75c5\u6bd2\u76f8\u95dc\u60e1\u6027\u816b\u7624\u4e4b\u7814\u7a76<\/td>\n2016\/7\/1~<\/p>\n

2017\/6\/30<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
10<\/td>\n\u8ca1\u5718\u6cd5\u4eba\u5de5\u696d\u6280\u8853\u7814\u7a76\u9662<\/td>\n\u7d30\u80de\u56e0\u5b50\u53d7\u9ad4\u884d\u751f\u4e4b\u5168\u65b0\u80dc\u80bd\u958b\u767c\u4ee5\u6291\u5236\u6d17\u814e\u767c\u708e\u53cd\u61c9\u53ca\u56b4\u91cd\u6557\u8840\u75c7\u4e4b\u7814\u7a76<\/td>\n2015\/9\/15~<\/p>\n

2016\/9\/14<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
11<\/td>\n\u79d1\u6280\u90e8<\/td>\nG-\u86cb\u767d\u5076\u5408\u53d7\u9ad4\u8207\u5176\u914d\u9ad4\u7d50\u5408\u6a5f\u5236\u65bc\u539f\u5b50\u8207\u5206\u5b50\u4f4d\u968e\u4e4b\u7406\u8ad6\u6a21\u64ec\u8207\u5be6\u9a57\u7814\u7a76<\/td>\n2015\/8\/1~<\/p>\n

2016\/7\/31<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n
12<\/td>\n\u79d1\u6280\u90e8<\/td>\n\u4ee5\u96fb\u8166\u6a21\u64ec\u65b9\u6cd5\u63a2\u8a0e\u8da8\u5316\u56e0\u5b50\u8207\u5176\u53d7\u9ad4\u4e4b\u4ea4\u4e92\u4f5c\u7528: \u671d\u5411\u5176\u7d50\u5408\u6a5f\u5236\u4e4b\u7406\u89e3\u8207\u6297\u767c\u708e\u80dc\u80bd\u85e5\u7269\u4e4b\u8a2d\u8a08\u958b\u767c<\/td>\n2014\/8\/1~<\/p>\n

2015\/7\/31<\/td>\n

\u4e3b\u6301\u4eba<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\uff0e\u8fd1\u5e74\u671f\u520a\u8ad6\u6587\uff1a<\/b><\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

\u5e8f\u865f<\/p>\n<\/td>\n

\n

\u984c\u76ee<\/p>\n<\/td>\n

\n

\u7d22\u5f15\u8cc7\u6599\u5eab<\/p>\n<\/td>\n

\n

\u767c\u8868\u5e74\u6708<\/p>\n

(\u51fa\u7248\u5e74\u6708)<\/p>\n<\/td>\n

\n

\u671f\u520a\u540d\u7a31<\/p>\n

(\u5377\u6b21:\u9801\u6b21 )<\/p>\n<\/td>\n

\n

\u4f5c\u8005<\/p>\n<\/td>\n<\/tr>\n

\n

1<\/p>\n<\/td>\n

Activation-Induced Conformational Changes of Dopamine D3 Receptor Promote the Formation of the Internal Water Channel<\/a><\/td>\nSCI<\/td>\n2017\/10<\/td>\nScientific Reports ,7:12792:1-14<\/td>\n\n

Wei-Hsiang Weng,<\/p>\n

\u00a0Ya-Tzu Li,<\/p>\n

Hao-Jen Hsu*<\/b><\/p>\n<\/td>\n<\/tr>\n

\n

2<\/p>\n<\/td>\n

Xanthohumol Suppresses Mylip\/Idol Gene Expression and Modulates LDLR Abundance and Activity in HepG2 Cells<\/a><\/td>\nSCI<\/td>\n2017\/9<\/td>\nJournal of Agricultural and Food Chemistry ,65:7908-7918<\/td>\n\n

Shih-Fen Chen,<\/p>\n

Pei-Yi Chen,<\/p>\n

Hao-Jen Hsu<\/b>,<\/p>\n

Ming-Jiuan Wu,<\/p>\n

Jui-Hung Yen*<\/p>\n<\/td>\n<\/tr>\n

\n

3<\/p>\n<\/td>\n

A Sequence in the loop domain of hepatitis C virus E2 protein identified in silico as crucial for the selective binding to human CD81<\/a><\/td>\nSCI<\/td>\n2017\/5<\/td>\nPLOS ONE<\/i>,12:0177383-0177383<\/td>\n\n

Chun-Chun Chang,<\/p>\n

Hao-Jen Hsu,<\/b><\/p>\n

Jui-Hung Yen,<\/p>\n

Shih-Yen Lo,<\/p>\n

Je-Wen Liou*<\/p>\n<\/td>\n<\/tr>\n

\n

4<\/p>\n<\/td>\n

Ribosome Protein L4 is essential for Epstein\u2013Barr Virus Nuclear Antigen 1 function<\/a><\/td>\nSCI<\/td>\n2616\/2<\/td>\nProc. Natl. Acad. Sci. USA. 113(8): 2229-2234<\/td>\n\n

CL SHEN,<\/p>\n

CD LIU,<\/p>\n

RI You,<\/p>\n

YH Ching,<\/p>\n

HC Chen,<\/p>\n

HJ Hsu<\/b>,<\/p>\n

JW Liou,<\/p>\n

CW Peng*<\/b><\/p>\n<\/td>\n<\/tr>\n

\n

5<\/p>\n<\/td>\n

\n

Peptides derived from CXCL8 based on in silico analysis inhibit CXCL8 interactions with its receptor CXCR1<\/a><\/p>\n<\/td>\n

SCI<\/td>\n2015\/12<\/td>\nScientific Reports ,5:18638:1-14<\/td>\n\n

SJ Jiang,<\/p>\n

JW Liou,<\/p>\n

CC Chang,<\/p>\n

Y Chung,<\/p>\n

LF Lin,<\/p>\n

HJ Hsu*<\/b><\/p>\n<\/td>\n<\/tr>\n

\n

6<\/p>\n<\/td>\n

Structure based computational assessment of channel properties of assembled ORF-8a from SARS-CoV<\/a><\/td>\nSCI<\/td>\n2015\/2<\/td>\nPROTEINS: Structure, Function, and Bioinformatics, 83:300-308<\/td>\n\n

HJ Hsu,<\/b><\/p>\n

MH Lin,<\/p>\n

C. Schindler,<\/p>\n

WB Fischer*<\/p>\n<\/td>\n<\/tr>\n

\n

7<\/p>\n<\/td>\n

Membrane undulation induced by NS4A of Dengue virus \u2013 a molecular dynamics simulation study<\/td>\nSCI<\/td>\n2014\/10<\/td>\nJ. Biomol. Struc. Dyn. 32: 1552-1652<\/td>\n\n

MH Lin,<\/p>\n

HJ Hsu,<\/b><\/p>\n

WB Fischer*<\/p>\n<\/td>\n<\/tr>\n

\n

8<\/p>\n<\/td>\n

In Silico Analysis Reveals Sequential Interactions and Protein Conformational Changes During the Binding of Chemokine CXCL-8 to its Receptor CXCR1<\/td>\nSCI<\/td>\n2014\/4<\/td>\nPLOS ONE<\/td>\n\n

Liou, J. W.<\/p>\n

Chang, F. T.<\/p>\n

Chung, Y.<\/p>\n

Chen, W. Y.<\/p>\n

Fischer, W. B.<\/p>\n

Hsu, H. J.*<\/b><\/p>\n<\/td>\n<\/tr>\n

\n

9<\/p>\n<\/td>\n

Membrane undulation induced by NS4A of Dengue virus \u2013 a molecular dynamics simulation study<\/td>\nSCI<\/td>\n2013\/8<\/td>\nJ. Biomol. Struc. Dyn.<\/td>\n\n

Lin, M.H.,<\/p>\n

Hsu, H.J.<\/b>,<\/p>\n

Bartenschlager, R.,<\/p>\n

Fischer, W.B.<\/p>\n<\/td>\n<\/tr>\n

\n

10<\/p>\n<\/td>\n

Computational modeling of the p7 monomer from HCV and its interaction with small molecule drugs<\/td>\nSCI<\/td>\n2013\/7<\/td>\nSpringer Plus<\/p>\n

2:324<\/td>\n

\n

Yi-Ting Wang,<\/p>\n

Hao-Jen Hsu,<\/b><\/p>\n

Wolfgang B Fischer<\/p>\n<\/td>\n<\/tr>\n

\n

11<\/p>\n<\/td>\n

Assembling viral channel forming proteins: Vpu from HIV-1<\/td>\nSCI<\/td>\n2013\/1(in press)<\/td>\nBiopolymers<\/td>\n\n

Li, L. H.<\/b>
\nHsu, H. J.<\/b>
\nFischer, W. B.*<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u8a31\u8c6a\u4ec1\u6559\u6388 \uff0e\u806f\u7d61\u65b9\u5f0f\uff1a\u6821\u5167\u5206\u6a5f2643\u3001\u5be6\u9a57\u5ba4\u5206\u6a5f2644 \uff0e\u8fa6\u516c\u5ba4\/\u5be6\u9a57\u5ba4\u4f4d\u7f6e\uff1aD904\/D92…<\/p>\n

\u7e7c\u7e8c\u95b1\u8b80<\/i><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"templates\/template-onecolumn.php","meta":{"footnotes":""},"class_list":["post-698","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/bmse.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/698","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bmse.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bmse.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bmse.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/bmse.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=698"}],"version-history":[{"count":1,"href":"https:\/\/bmse.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/698\/revisions"}],"predecessor-version":[{"id":2431,"href":"https:\/\/bmse.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/698\/revisions\/2431"}],"wp:attachment":[{"href":"https:\/\/bmse.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=698"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}